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You don't need a large space for your store. Usually 50mb is enough. Most hosting now will support php. You can use some shopping cart written in php. Usually such hosting will cost less than $10/mo.
Then you need a supplier. Finding a good suppliers is important. A good place to find wholesalers is thomasregister.com. You can type the product you like and it will give the manufactures or wholesalers of the product. There will be the phone number, fax and emails of the wholesalers.
Another good thing to have it sells on online auctions is that you have another option to sell your product. Many people actually make their living as a seller on ebay. So if your product sells, you don't necessarily need set up an online store. You can actually just sell it on ebay.
A good place to check the market is keyword suggestion tool. The most popular one is the overture suggestion tool. You type in a word and it will tell you how many searches of the word in the last month on overture. Since overture covers most popular search engines like yahoo, msn, altvista and so on, it will give you a good idea that how good the online market is for the keyword. A good market should have at least 1000 search for the keyword you typed in.
The first year I am in the online business, I build two websites. But actually they were making little money. But I learned a lot from the experience. The second year, I still didn't make a lot of money. But the good thing is I was about to make my living. There are more than a lot websites on the net. But I can say, most of actually making no money. The reason is they didn't do things right.
After you decided to go for an online store. You need to build your store. You need to register for a domain. You have to have your own domain because you don't want marketing somebody else's domain. After you registered your domain, you need to buy an hosting for your store.